Waterhouse was born in Hammersmith, London, and was raised in Chiswick, London, the daughter of Elizabeth, a cancer care nurse, and Norman Waterhouse, a plastic surgeon. She has a brother named Charlie,[6] and two younger sisters, Madeleine and Imogen (“Immy”), who are also models and an actress, respectively.
Waterhouse began her modelling career after being discovered in, as she said in a vogue video, ‘either a topshop or H&M’ in London when she was 16. When she was 19, she became a lingerie model for Marks and Spencer.
